It’s not possible unless you’re someone like Rodney Dangerfield. But even he couldn’t make any headway if his image was being a pussy. See, it’s all about the image. Since these people won’t respect you as an equal, you can’t really put them down much.
So since you can’t humiliate a bully – the best thing is to beat him up harshly or stay from him!
If someone can make comebacks to bullies, please share some and whether they were effective or not.